Objective: To evaluate the reinforcing factors that supporting female genital cutting among student nurses. Setting: The study was conducted at the Faculty of Nursing, Benha University. Design: A descriptive study was followed. Subject: male and female student nurses whom attending the first academic year 2012. Size: 220 student nurses (80 male and 140 female). Tool: An Arabic interviewing questionnaire was developed and used to assess the general characteristics, student nurses' knowledge about concept, complication, consequences, and factors that affecting the reinforcing of FGC among Egyptian male and female nurse students. Results: The present study results revealed that, 52.5% and 80.7% of male and female students respectively had incorrect knowledge regarding concept, complications and consequences of FGC, the difference is statistically highly significant (p