Osteoporosis is a significant public health problem with serious consequences. The aim of this study was to assess the risk factors of osteoporosis among working women, and develop health educational guidelines to prevent/reduce osteoporosis at Benha City. Research design: A descriptive correlation research design was utilized to conduct the study. Setting: The study was conducted at two Toshiba Elaraby Factories, they named; Benha Toshiba Elaraby’ factory at Qaluobia Governorate, and Quesna Toshiba Elaraby’ factory at Elminofyia Governorate. The sample included 10% from 3650 working women (365) working women they were selected as randomly from the above mentioned setting. Tools: One tool was developed by the researchers: Osteoporosis structured interviewing questionnaire: It consisted of six parts: Part I: Concerned with socio-demographic characteristics of the working women. Part II: Concerned with the obstetric history Part III: history of osteoporosis. Part IV: Medical and family history Part V: assess the Women's' knowledge about osteoporosis disease Part VI: risk factors of osteoporosis and life style: Results of this study showed; the highest percentages of women were found within age groups from 40-49 years (36.4%). Postgraduate's education represented the highest percentage (34.8%), only 7.7 were continuous movement. and 75.3% are from rural area. 63.3% of working women had good total knowledge score. 77.8% of the study subjects are suffering from osteoporosis. 63.3% had family history of osteoporosis. This study concluded that the common risk factors identified were; family history, lack of exercises, irregular exposure to sunlight, and insufficient taken protein and vitamin D. Also; osteoporosis health guideline were needed for prevention/ reduction of osteoporosis. The study recommended community based health programs on osteoporosis that targeted a wide audience should be implemented. 3- further studies are needed to evaluate the effect of osteoporosis health guideline in the prevention of osteoporosis.