The nursing students get more personal and social self-esteem through the learning environment. This study aim was to assess the relation between educational environment on self-esteem of nursing students at the Faculty of Nursing Zagazig University. It was conducted using a cross-sectional design on a stratified random sample of 268 students in second, third, and fourth years. Two tools were used for data collection, namely; Rosenbergs elf-esteem scale and educational environment questionnaire. The study findings revealed that one-half of the nursing students (50%) had low agreement upon the total educational environmental factors. And the majority of the nursing students (84%) were having high self-esteem. It concluded that there are a positive significant correlation between nursing students’ self-esteem scores and their agreement upon many of the areas of the educational environment. The study recommends improvement of the educational environment of nursing students, particularly in the arenas of the skills lab, classrooms, and auxiliary and recreational facilities, and student assessment. Students’ self-esteem needs some consideration, especially for male and junior students through training and counseling helps. Further research is suggested to assess the effect of improving the learning environment of nursing students on their self-esteem.