Staff Members - Benha University
The Plasmid Praw Extends the Spectrum of Defense Genes of Mycobacterium marinum
Global Veterinaria • 2018
Publication Information
Authors
Salma A. Shoulah, Abdelfattah Selim,
Faysal Hamouda, Elsayed Galila and Astrid Lewin
Keywords
Mycobacterium Conjugative Plasmid Gene Function Analysis COG Categories Defense
Genes
Journal
Global Veterinaria
Publisher
Not Available
Volume
20
Issue
Not Available
Pages
6-10
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Only a few conjugative plasmids from Mycobacteria have so far been identified and the assessment
of their contribution to mycobacterial virulence is hampered by restricted knowledge of the functions of the
plasmid genes. That also applies to the conjugative plasmid pRAW from Mycobacterium marinum.
Bioinformatic tools nowadays facilitate prediction of gene functions. In this study we assigned COG (Clusters
of Orthologous Groups of protein) groups to all 98 genes from pRAW including those that were annotated as
“hypothetical” to contribute to functional characterization of genes from this conjugative plasmid.
of their contribution to mycobacterial virulence is hampered by restricted knowledge of the functions of the
plasmid genes. That also applies to the conjugative plasmid pRAW from Mycobacterium marinum.
Bioinformatic tools nowadays facilitate prediction of gene functions. In this study we assigned COG (Clusters
of Orthologous Groups of protein) groups to all 98 genes from pRAW including those that were annotated as
“hypothetical” to contribute to functional characterization of genes from this conjugative plasmid.