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publication name Mathematical Evaluation of Thermal Retinal Damage after Laser Exposure in Chicken Eyes
Authors EHAB I. MOHAMED, SAMERA M. SALLAM, ALAH E. HAMZA, EL–SAYED M. EL–SAYED
year 2008
keywords Arrhenius; Dielectric Conductivity; Ionic Activation Energy; Relaxation Activation Energy
journal Journal of Biophysics and Biomedical Sciences
volume 1
issue 2
pages 75-79
publisher Not Available
Local/International International
Paper Link Not Available
Full paper download
Supplementary materials Not Available
Abstract

Laser photocoagulation therapy is widely employed for the treatment of many human–eye retinal dis-eases, yet the technique is not hazard-free and unfavorable results and/or variable success outcomes may pur-sue; depending on laser type, wavelength and method of application. The purpose of the present study was to evaluate mathematically the laser–induced retinal damage and recovery after laser exposure in chicken eyes. Thirty-five chickens were divided into 7 equal groups: a control unexposed group, an immediately decapitated group after exposure, and five decapitated groups on consecutive recovery days 1, 2, 3, 4, and 5; respectively. Dark adapted chicken eye was exposed to Argon laser (488 nm, 1 mW/cm2 ; 0.12 sec duration) and the electri-cal conductivity was measured for chicken retina at temperatures 10, 20 and 30 °C. The retinal thermal damage induced by the ionic activation energy Ωw(t) and by the relaxation activation energy Ωr(t) was evaluated using an Arrhenius formula for all study groups. Results showed that, after thermal retinal damage by laser exposure in the first two days, recovery was attained in the next four days.

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