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Serum level of Golgi protein(73) as a diagnostic marker for hepatocellurlar carcinoma
Benha Medical Journal • 2017
Publication Information
Authors
Fawzy M. Khalill,Sherif I. Negm, Mohamed A. El Assal, Anas A. Yousif, Raafat S.Salem
Keywords
GP (73), AFP , liver cirrhosis ,HCC .
Journal
Benha Medical Journal
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Background :Golgi protein 73 (GP73) as a potential serum marker for hepatocellular carcinoma (HCC) has not been validated in studies.The aim: of this study was to determine the value of serum GP73 in the diagnosis of HCC.
Subject and Methods: Serum GP73 and alpha-fetoprotein (AFP) were compared in a total of 80 human subjects in this study ,(35) with HCC, (35) patients with cirrhosis and( 10) healthy controls were included .
Results: Using 10.3 relative units as a cut-off value, the sensitivity and specificity of serum GP73 for HCC were 97.1% and 85.7% ,compared with 57% and 55.6% for AFP (p
Subject and Methods: Serum GP73 and alpha-fetoprotein (AFP) were compared in a total of 80 human subjects in this study ,(35) with HCC, (35) patients with cirrhosis and( 10) healthy controls were included .
Results: Using 10.3 relative units as a cut-off value, the sensitivity and specificity of serum GP73 for HCC were 97.1% and 85.7% ,compared with 57% and 55.6% for AFP (p