In this work, phytochemical examination of fresh juice and methanolic peel, pulp extract revealed the presence of diverse bioactive organic components. The antioxidant activity of Citrus sinensis L. (Sweet Orange) juice extract (JE) and crude methanolic extract of pulp and peel (MPPE) were tested. Two fungal strains and six bacterial strains (3 gramme positive and 3 gramme negative) were tested. Citrus sinensis plant extracts show antibacterial action against both bacterial strains, according to the research, but there is no efficacy against fungal strains. MPPE has higher antibacterial activity than J.E, this may be because phenolic and flavonoid compounds are found.