Premenstrual syndrome (PMS) is one of commonly health problems which affected on 30% to 40% of female adolescents. Our target was evaluating the effects of educational life style intervention for management of premenstrual tension syndrome between adolescent student. The current study hypothesized that: Life style intervention will be effective for management of PMS symptoms between adolescent students. Design: Aquasi design utilized to fulfill our aims. Investigation was conducted on 170 adolescent students have PMS at time of collecting data at Nursing Institute in Benha Teaching Hospital and Health Insurance Hospital on Three tools used: structured interviewing questionnaire, premenstrual assessment scale and life style assessment tool. Significant differences in mean score of PMS symptoms were observed of sample at pre /post intervention. Also there was highly positive correlation among PMS and life style in students either pre or post intervention. Our conclusion, research hypothesis was supported and life style intervention was effective for management of PMS among adolescent students. The study recommended nursing curriculum most updated for contain comprehensive information regarding PMS and effect of life style modification for managing it.