Salinity is a crucial constraint that slow downs agriculture production in many areas in Egypt. Inoculation with plant growth promoting microorganisms may enhance plant growth under salt stress conditions. The objective is to evaluate the inoculation efficieny of biostimulant strains (Pseudomonas fluorescence D23, Bacillus pumilus DI39 and Azospirillum lipoterum D178), humic acid and organic manure (compost) on growth and yield of tomato (Solanum lycopersicum L.). This experiment was conducted in greenhouse conditions at the Experimental Farm Station of Faculty of Agricuture Moshtohor during 201 1. The highest significant increase of dehydrogenase, nitrogenase and phosphatase was observed in tomato inoculated with biostimulant combined with humic acid + compost at one and half dose. The highest records of macronutrients uptake by tomato shoots were observed when tomato amended with biostimulant combined with compost at different doses + humic acid. Application of humic acid combined with compost significantly decreased the proline content in tomato, whereas, the reverse was observed in nitrate reductase. Dual treatment of tomato with biostimulant and compost gave higher records of tomato growth characteristics and yield.