The influence of inoculation with mycorrhizal fungi and phosphate solubilizing bacteria in the presence of associative N2-fixers (Azospiriilum brasilense) on wheat (Sakha 8 cultivar and soil fertility was studied. Inoculation of wheat grains with phosphate solubilizing bacteria (PSB) gave the highest counts of Azospirilla.Dehydrogenase activity of the soil was higher in the VAM treatments. Also- organic carbon. ammoniacal and nitrate nitrogen. total and available phosphorus' nitrogen and potassium were higher in the tested soil when wheat grains were inoculated with VAM compared with phosphate solubilizing bacteria. . The inoculation with VAM gave higher values of N, p and K concentrations in wheat plants compared with the inoculation with PSB. There was significant difference in spike weight, grain weigh /spike, ,root system length and dry weight of root and shoot system/plant which were highly significant in the presence of VAM compared with phosphate solubilizing bacteria. In contrary there is no significant difference in studied growth characters and grain yield of wheat when superphosphate or rock phosphate was used as phosphorus fertilization in the presence of microbial inocula.