Introduction: Neonatal pre-feeding responses (NFR) that appear in newborns before the first feed are play an important role in their development. The pattern and diversity of these PFR need to be further investigated. Aim: To examine the patterns and factors associated with NFR in relation to delivery practices, breastfeeding practices and later development. Methods: We examined NFR among 90 infants, 45 who were delivered by cesarean section delivery (CSD) and 45 underwent vaginal delivery (VD). Data related to antenatal care, age, parity, gravidity, health related complications in mother, exclusive breastfeeding (EBF) and breastfeeding frequency (BFF) and duration of continued breastfeeding in previous child (CBF). Type of C-section; elective versus emergency and duration of VD were taken into consideration. Other information included previous breastfeeding practices. Results: We identified 13 NFR. The grasp response was the most common NFR (68.9%) in vaginal and attempting to turn head was commonest in CSD (64.4%). and sucking at breast were significantly associated with EBF and developmental scores (in VD only) (r0.3 at P