Staff Members - Benha University
518 Received: 13/10 /2020 Accepted: 1/12/2020 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY-SA) license (http://creativecommons.org/licenses/by/4.0/) Pediatric COVID-19 Infection: Do Clinical Features and Hematological Parameters Predict the Need for ICU Admission?
• 2021
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Authors
Shaimaa Reda Abdelmaksoud1*, Rana Atef Khashaba2, Rasha Shaker Eldesouky3, Effat Assar1
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publication.type
Local
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Abstract
The world is facing the new pandemic caused by SARS-COV2. The confrontation of this new pandemic necessitates study and analysis of the clinical and laboratory finding in such entity.
Objectives: To discuss the clinical and hematological findings in pediatric patients with SARS-CoV-2 infection and to correlate these characters with the need for ICU admission.
Patients and methods: This was a hospital record-based study, in which the clinical features and laboratory findings of 29 pediatric patients with confirmed COVID-19 infection were obtained from the medical records of admitted pediatric patients.
Results: This study included 29 pediatric patients with confirmed COVID-19 infection. Six cases (20.7%) were admitted to pediatric ICU. The most common presenting symptoms were cough in 23 cases (79.3%) and fever in 19 cases (65.5%). There was a significant association between tachypnea and ICU admission; as 5 out of 6 ICU cases (83.3%) had tachypnea compared to none 0/23 (0.0%) of the non ICU patients (P < 0.001). The frequencies of lymphopenia and thrombocytopenia were higher among ICU patients (100.0% and 50.0% respectively) than the non ICU ones (39.1% and 8.7% respectively) (P < 0.05 for both). The median values of lymphocytes and platelets counts were significantly lower in ICU patients than those of non ICU patients (P=0.002 and 0.007 respectively). CRP values were higher in ICU patients compared to non ICU patients (P=0.011).
Conclusion: Decreased lymphocyte count, thrombocytopenia and elevated CRP can be stood out as discriminative laboratory indices for early ICU admission.
Objectives: To discuss the clinical and hematological findings in pediatric patients with SARS-CoV-2 infection and to correlate these characters with the need for ICU admission.
Patients and methods: This was a hospital record-based study, in which the clinical features and laboratory findings of 29 pediatric patients with confirmed COVID-19 infection were obtained from the medical records of admitted pediatric patients.
Results: This study included 29 pediatric patients with confirmed COVID-19 infection. Six cases (20.7%) were admitted to pediatric ICU. The most common presenting symptoms were cough in 23 cases (79.3%) and fever in 19 cases (65.5%). There was a significant association between tachypnea and ICU admission; as 5 out of 6 ICU cases (83.3%) had tachypnea compared to none 0/23 (0.0%) of the non ICU patients (P < 0.001). The frequencies of lymphopenia and thrombocytopenia were higher among ICU patients (100.0% and 50.0% respectively) than the non ICU ones (39.1% and 8.7% respectively) (P < 0.05 for both). The median values of lymphocytes and platelets counts were significantly lower in ICU patients than those of non ICU patients (P=0.002 and 0.007 respectively). CRP values were higher in ICU patients compared to non ICU patients (P=0.011).
Conclusion: Decreased lymphocyte count, thrombocytopenia and elevated CRP can be stood out as discriminative laboratory indices for early ICU admission.