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Video electroencephalography and the serum levels of Interleukin-6 in patients with refractory epilepsy

• 2019
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Publication Information
Authors Abo Zeid Abdallah Khodeir,Kamel Mahmoud Ali Hewedi,Abdelnaser Ali Mourad,Shaimaa Mohamed Kasem,Raghdaa Abdel-khaleq Abdel-halem
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publication.type Local
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Abstract
: there is increasing evidence of a complex relationship between epilepsy and the immune system.

Objective: The aim of this study was to determine that there is a chronic inflammatory process underlying pathophysiology of refractory epilepsy by determining the level of interleukin-6 (IL-6) in patients with refractory epilepsy and its relation to different poor prognostic factors that predict refractoriness.

Patients and methods: this study was conducted on 80 patients with refractory epilepsy and 80 healthy control participants. All patients were assessed using detailed clinical history, examination, routine laboratory tests, C reactive protein, brain imaging, Video electroencephalography and IL-6 level in serum.