This study was conducted among the staff members of Zagazig University, Benha Branch. The sample included 110 members from Faculties of Engineering, Sciences, Literature and Commerce. Another 38 subjects have been selected as a control group from the management sectors of the previous faculties. Subjects of both groups were subjected to assessment of work stress, mental health, behavioral reactions to stress and physical health. Conflicts, job pressure and job scope constituted the main problems among the staff members (38.18%, 34.55% and 37.27% respectively), while rapport with management was the main problem among the control (44.74%) subjects of practical faculties suffered more from work related stress. More females complained of being more dissatisfied with their job (37.5%) if compared to males (33.87%). Also mental health traits, and the prevalence of some stress related behavioral reactions and symptoms appeared to be higher among the staff members than among the control group.