Staff Members - Benha University
Comparison Treatment of Vitiligo by Co-culture of Melanocytes Derived from Hair Follicle with Adipose-Derived Stem Cells with and without NB-UVB
• 2017
Publication Information
Authors
Ahmed A Saleh1, Osama H Abdel-salam1, Hala G Metwally2, Hany A Abdelsalam1, Ayman M Hassan3 and Walaa S Sosa1*
Keywords
Vitiligo; Skin transfers; Depigmentation; Topical steroids;
Cellular grafting
Journal
Not Available
Publisher
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Volume
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Issue
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Pages
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Objective: The aim of this work is to evaluate treatment of vitiligo by co-culture of melanocytes derived from hair
follicle with adipose-derived stem cells with (NB-UVB) and without (NB-UVB).
Patients and methods: In this study, we used co culture of adipose derived stem cell with melanocytes derived
from hair follicle in treating different types of stable resistant vitiligo, by two methods transplantation: group (A)
exposed to (NB-UVB), group (B) did not expose to (NB-UVB). They are followed up for 3 months.
Results: At the end of the follow up period which was 3 months group (A) showed better pigmentary response
than group (B) and it was highly statistically significant. Stability, size, site and onset of vitiligo appeared to be
important factors affecting treatment results. Using (NB-UVB) also after injection of the treatment showed more
improvement in the treatment results.
Conclusion: Co-culture of adipose derived stem cell with melanocytes derived from hair follicle could be a safe
and effective method of treatment for stable localized vitiligo in patients resistant to other methods of therapy.
follicle with adipose-derived stem cells with (NB-UVB) and without (NB-UVB).
Patients and methods: In this study, we used co culture of adipose derived stem cell with melanocytes derived
from hair follicle in treating different types of stable resistant vitiligo, by two methods transplantation: group (A)
exposed to (NB-UVB), group (B) did not expose to (NB-UVB). They are followed up for 3 months.
Results: At the end of the follow up period which was 3 months group (A) showed better pigmentary response
than group (B) and it was highly statistically significant. Stability, size, site and onset of vitiligo appeared to be
important factors affecting treatment results. Using (NB-UVB) also after injection of the treatment showed more
improvement in the treatment results.
Conclusion: Co-culture of adipose derived stem cell with melanocytes derived from hair follicle could be a safe
and effective method of treatment for stable localized vitiligo in patients resistant to other methods of therapy.