Geese meat is rich in fat and cholesterol thus people whom favorite it are at risk for coronary heart disease which consider the major cause of morbidity between them. For this purpose thirty geese of one month old were divided into two equal groups. The first group act as control fed on basal ration. The second group fed on ration containing fish oil at a concentration of 4% for three months. Blood samples were collected from five geese of each group during slaughtering at one, two and three months for preparation of serum and erythrocyte hemolysate. Serum samples were used for determination of total lipid, total cholesterol triacylglycerol (TG), phospholipids, HDLc, LDLc, VLDL, NEFA Malondialdehyde (MDA) level and fatty acid pattern. Erythrocyte hemolysates were used for estimation of sodium, potassium, calcium and phosphorous. Liver specimens were also collected, homogenized and prepared for determination of cholesterol and TG. The obtained data revealed significant decrease in liver and serum total cholesterol, TG, serum total lipids LDLc, VLDL at the second month. This decrease became highly significant in TG and LDLc at the third month of fish oil administration. Serum MAD level revealed highly significant increase compared with control group. HDLc, and erythrocyte phosphorous, calcium, potassium and sodium, showed non significant changes in fish oil feeding group at all time of the experiment, while NEFA phospholipids showed significant decrease at the third month only. Chromatographic separation of fatty acid pattern revealed marked increase in linolenic while linoleic acids was decreased with a low percentage of total saturated to total unsaturated fatty acids .Thus it was advised to supply fish oil to rations of geese to reflect its benefit effects on consumer health.