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publication name Genetic Expression of High Mobility Group Box 1 in Neonatal Sepsis
Authors Omima M. Abdel Haiea , Mona A. Elbesherya , Shuzan A. Mohammedb , Salwa S. Huseinc , Neveen T. Abeda
year 2023
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Abstract

Background: High-mobility group box 1 (HMGB1) has important role in a variety of diseases, including neonatal sepsis (NS). The aim of this study is to evaluate the clinical importance of HMGB1 genetic expression in NS demonstrating its diagnostic value and detecting the effect of its genetic expression on the disease outcome. Patients and Method: This study was carried out on 100 neonates; 28 neonates with clinical sepsis and had positive blood cultures (confirmed), 22 neonates with clinical sepsis but had negative blood cultures (suspected) and 50 healthy non-infected newb

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