Staff Members - Benha University
Genetic Expression of High Mobility Group Box 1 in Neonatal Sepsis
• 2023
Publication Information
Authors
Omima M. Abdel Haiea
, Mona A. Elbesherya
, Shuzan A. Mohammedb
, Salwa S. Huseinc
, Neveen
T. Abeda
Keywords
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Journal
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Publisher
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Volume
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Issue
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Pages
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publication.type
Local
Paper Link
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Supplementary Materials
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Abstract
Background: High-mobility group box 1 (HMGB1) has important
role in a variety of diseases, including neonatal sepsis (NS). The aim of
this study is to evaluate the clinical importance of HMGB1 genetic
expression in NS demonstrating its diagnostic value and detecting the
effect of its genetic expression on the disease outcome. Patients and
Method: This study was carried out on 100 neonates; 28 neonates with
clinical sepsis and had positive blood cultures (confirmed), 22
neonates with clinical sepsis but had negative blood cultures
(suspected) and 50 healthy non-infected newb
role in a variety of diseases, including neonatal sepsis (NS). The aim of
this study is to evaluate the clinical importance of HMGB1 genetic
expression in NS demonstrating its diagnostic value and detecting the
effect of its genetic expression on the disease outcome. Patients and
Method: This study was carried out on 100 neonates; 28 neonates with
clinical sepsis and had positive blood cultures (confirmed), 22
neonates with clinical sepsis but had negative blood cultures
(suspected) and 50 healthy non-infected newb