Staff Members - Benha University
DISTURBED SERUM SPHINGOSINE-1-PHOSPHATE LEVELS COULD PREDICT DISTURBED LIVER AND KIDNEY FUNCTIONS IN APPARENTLY HEALTHY PERSONS CHRONICALLY EXPOSED TO FUMONISINS
THE EGYPTIAN JOURNAL OF MEDICAL SCIENCES • 2022
Publication Information
Authors
Noha Soliman Elnajjar, Yasmin Mohammed Marei
Keywords
Not Available
Journal
THE EGYPTIAN JOURNAL OF MEDICAL SCIENCES
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
Local
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Objectives: The current study tried to
determine the effects of exposure to
fumonisins on kidney and liver func-
tions tests and sphingolipid metabo-
lites.
Patients & Methods: 80 apparently
healthy participants of Area 1(A1)
that was considered as area heavily
contaminated by fumonisins and Area
2 (A2) that was considered as low con-
tamination area. Ten urban volunteers
were enrolled as a control group. All
participants underwent full history
taking, complete clinical examination
with special regard to liver and kidney
and gave blood samples for estimation
of serum levels of aspartate transami-
nase (AST), alanine transaminase
(ALT), urea, creatinine, and plasma
lipid profile, and ELISA estimation of
plasma sphingosine-1-phosphate (S1P)
levels
determine the effects of exposure to
fumonisins on kidney and liver func-
tions tests and sphingolipid metabo-
lites.
Patients & Methods: 80 apparently
healthy participants of Area 1(A1)
that was considered as area heavily
contaminated by fumonisins and Area
2 (A2) that was considered as low con-
tamination area. Ten urban volunteers
were enrolled as a control group. All
participants underwent full history
taking, complete clinical examination
with special regard to liver and kidney
and gave blood samples for estimation
of serum levels of aspartate transami-
nase (AST), alanine transaminase
(ALT), urea, creatinine, and plasma
lipid profile, and ELISA estimation of
plasma sphingosine-1-phosphate (S1P)
levels