| publication name | EFFECTS CF SILDENAFIL ON COPULAT ORY BEHAVIOUR IN SEXTALLY INACTIVE MALE RATS |
|---|---|
| Authors | Nasr N. Zaki |
| year | 2002 |
| keywords | |
| journal | Z. U. M J.Accepted in Pan Arab Society Of Andrological Science., Damascus Syria, in December 2002 |
| volume | 8 |
| issue | 4 |
| pages | 396-412 |
| publisher | Not Available |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
The prescnt srudf investtsates &e effecs induccd b1' sildenafil (0.004 and 0.(X)8 mg/gm' p.o.) on copulatory- beberior of malc rers. performed on serue- inactive male rat model against sexually highl;- receptive femaler -{L.o. h reri.$s currart eridencr rcgilditrC its central sexual effect on decreased desire (libido) arousal difficuhits erd orgasm- Parametcn of sexuil behavior were assessed including mount' intromission, and ejrcularion htencies ud frequeacitt Als*. serum follicle-stimulating hormoqe (FSH), luteinizino hormone (LH) lnd prolactil lereb r*-cre chccked ia serually inacth-e rats in comparison to control end normel intrct rrrs The d.rte obteined shor that sildeuafil modifies both sexual arousal and ejaculator-v mcchanisms of copulation It epptan thrt althougi it induced a facilitatory effect on ejacularion of all rets- the hncring of ejaculetor.v thrcshold was achieved by means of a reduction of mount frequenc.v and intromirsion frequencf in both scruallf inactiv-e rats and those rvith normal serual actiriS'. Sildenelil iacrustd scruel rrous:|. itr both seruallf inactive and rats with normal serual acthir;-. It was fouod tbt. i! scrualll- inctive nt modcl there trs a statisticall-r- significant decrease in mount, htromission end ejecalation htencies (P4.05 ; P4.05 and p