Dandruff is a chronic condition that can almost always be controlled, it is a common scalp disorder, and it can be an embarrassing hair problem. The aim of this study was to evaluate the effect of nursing guidelines on hair dandruff symptoms for adult patients. Design: A quasi-experimental design was used to conduct this study. Setting: The study was conducted at the Dermatology Outpatient Clinic of El-Demerdash Hospital in Ain Shams University. Sampling: A purposive sample including 72 hair dandruff adult patients, which represent 20% of last year attended adult patients' complaining from this problem. Tool: A structured interview questionnaire included demographic characteristics of hair dandruff patient, current symptom, patient’s knowledge and practices regarding their hair dandruff. Results: the study group included 16.6% males and 83.4% females. The mean age was 27.6±6.1, the patients' entire symptoms improved after implementation of nursing guidelines instructions, with highly statistically significant differences between pre/post guidelines implementation (p