| publication name | “Study of Labelling and Stability of 188Re-NTMP Complex”; Arab Journal of Nuclear Science and Applications, 39(2): 44-51(). |
|---|---|
| Authors | M.T. El-Kolaly, M.A. Motaleb, and M.Y. Nassar |
| year | 2006 |
| keywords | |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | Local |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Labeling of nitrilotris(methylene phosphonic)acid (NTMP) with rhenium-188 using stannous chloride as a reducing agent was investigated. Dependence of the yield of the 188Re-NTMP complex on the concentration of the reducing agent, pH, reaction time, temperature, ascorbic acid and amount of carrier added was studied. Under optimum conditions, the labeling yield of 188Re-NTMP complex was 90% for the carrier-free 188Re but with the carrier-added 188Re the labeling yield was more than 97%. Furthermore, the stability of the 188Re-NTMP complex against pH change and dilution with saline was also studied. It was found that the addition of carrier stabilized the 188Re-NTMP complex against pH change and dilution.