| publication name | Folic Acid Intake and Neural Tube Defects: Two Egyptian Centers Experience |
|---|---|
| Authors | Mortada H. El-Shabrawi, MD, Naglaa Mohamed Kamal, MD, Mona Abbas Elhusseini, MD, Laila Hussein, MD, Enas Abdallah Ali Abdallah, MD, Yahia Zakaria Abdelalim Ali, MD, Ahmed Abelfattah Azab, MD, Mostafa Abdelazim Salama, MD, Muna Kassab, MD, and Michael Kr |
| year | 2015 |
| keywords | NTDs = neural tube defects, RDA = recommended daily allowance, USDA = U.S. Department of Agriculture, FDA = Food and Drug Administration. |
| journal | Medicine |
| volume | 94 |
| issue | 37 |
| pages | e1395 |
| publisher | Wolters Kluwer Health, Inc. |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Neural tube defects (NTDs) are a group of congenital malformations with worldwide distribution and complex etiopathogenesis. Folic acid plays a pivotal role in their prevention. We aimed to identify the protective effect of folic acid intake against NTDs and its dependence on different socioeconomic and environmental factors in a cohort of mothers in Egypt. A cross-sectional study was carried over a period of 12 months on mothers who gave birth to babies with NTDs (group 1) and a control group with healthy offsprings (group 2). Both groups completed 2 questionnaires: food frequency questionnaire targeting the daily folate intake, and socioeconomic status and medical history questionnaire. Both groups of mothers received folate