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Cadmium Status Among Pediatric Cancer Patients in Egypt

medcine • 2015
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Publication Information
Authors Sherief, Laila M.; Abdelkhalek, Elhamy R.; Gharieb, Amal F.; Sherbiny, Hanan S.; Usef, Doaa M.; Almalky, Mohamed A.A.; Kamal, Naglaa M.; Salama, Mostafa A.; Gohar, Wafaa
Keywords Not Available
Journal medcine
Publisher Wolters Kluwer Health, Inc
Volume 94
Issue 20
Pages e740
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Cadmium (Cd) is a toxic, nonessential, and bio-accumulating heavy metal widely used in industry. Several studies have suggested a positive association between Cd exposure and risks of several cancers. However, data from general population, especially children are sparse.

In the current cross-sectional case–control study, we aimed to assess the association between Cd exposure, as expressed by Cd body status (blood, urine, scalp hair, and nails) and cancer among Egyptian children. Three hundred and fifty pediatric cancer cases aged 3 to 14-years old were enrolled in our study. Their body Cd levels were evaluated using Atomic Absorption Spectrophometer and were compared with Cd levels of 350 healthy children.

Significantly higher Cd levels (blood, urine, scalp hair, and nails) were documented in cancer cases when compared with control (P