In this work, we studied of variable viscosity, Dufour and Soret effects on free convection heat and mass transfer of a non- Newtonian power-law fluid over a vertical full cone in a saturated porous medium in the presence of chemical reaction, non uniform heat generation and thermal radiation. The transformed nonlinear ordinary differential equations are solved numerically using the fourthorder Runge-Kutta method coupled with the shooting method. The influences of various parameters on the local Nusselt number and the local Sherwood number are presented and discussed.