Staff Members - Benha University
Characterization of peroxisome proliferator-activated receptor at different stages of development of intestine, liver, spleen, pancreas and posterior kidney of the loach (Misgurnus anguillicaudatus)
Egyptian Journal of Aquatic Biology & Fisheries • 2021
Publication Information
Authors
Mona N. Hussein; Xiaojuan Cao; Amel M. El Asely
Keywords
PPARα, PPARγ, Fish, immunohistochemistry
Journal
Egyptian Journal of Aquatic Biology & Fisheries
Publisher
www.ejabf.journals.ekb.eg
Volume
25
Issue
4
Pages
87-104
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
The loach is one of the most important fish species in aquaculture in China.
The study of peroxisome proliferator-activated receptors (PPARs) will be
essential for the determination of the functional role of the PPARα and
PPARγ in loach fish. We used immunohistochemistry for PPARα and
PPARγ at some stages of development beginning from the age of 1 month
till the age of 15 months. Our result indicated that, the expression of
PPARα and PPARγ was found in; columnar cells lining intestinal folds,
hepatocytes, blood sinusoids in liver, pancreatic islets, pancreatic acini, the
whole spleen and epithelial cells lining renal tubules of the kidney. The
expression pattern of both PPARα and PPARγ was low at the age of one
month, then reach its highest level at the age of 2 months. Then it decline at
the age of 5 months. Then it re-increase at the age of 7 months and became
low in older ages. The expression of PPARα was higher in comparison with
PPARγ.
The study of peroxisome proliferator-activated receptors (PPARs) will be
essential for the determination of the functional role of the PPARα and
PPARγ in loach fish. We used immunohistochemistry for PPARα and
PPARγ at some stages of development beginning from the age of 1 month
till the age of 15 months. Our result indicated that, the expression of
PPARα and PPARγ was found in; columnar cells lining intestinal folds,
hepatocytes, blood sinusoids in liver, pancreatic islets, pancreatic acini, the
whole spleen and epithelial cells lining renal tubules of the kidney. The
expression pattern of both PPARα and PPARγ was low at the age of one
month, then reach its highest level at the age of 2 months. Then it decline at
the age of 5 months. Then it re-increase at the age of 7 months and became
low in older ages. The expression of PPARα was higher in comparison with
PPARγ.