| publication name | Chromophobe Renal Cell Carcinoma, Oncocytoma and Clear Cell Carcinoma: A Compartive Immunohistochemical Study |
|---|---|
| Authors | MOHAMMED ABD ELHAMID, M.Sc.*; MOHEBAT H. GOUDA, M.D.*; TAGHREED ABD ELSAMEE, M.D.*; NEHAL S. ZAFER, M.D.* and MAHMMOUD ELBAZ, M.D. |
| year | 2020 |
| keywords | |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | Local |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Background: Renal oncocytoma, chromophobe RCC, and conventional RCC (granular cell type) have different prognosis. The differentiation between them sometimes is difficult and may cause a diagnostic dilemma. Aim of Study: To reveal the better immunohistochemical diagnostic markers for differentiation between Chromophobe Renal Cell Carcinoma (ChRCC), Clear Cell Renal Cell Carcinoma (CCRCC), and oncocytoma. Material and Methods: We reviewed one hundred and fifty cases of renal cell carcinoma: ChRCC (100 case), CCRCC (25 cases) and RO (25 cases). We carried out comprehensive immunohistochemical profiling using Hales Colloidal Iron stain (HCI), and 6 markers: Vimentin, CK7, CD10, CD117. EpCAM, and S100. Results: Our results demonstrated a statistically significant difference in the expression of Hales colloidal iron among the studied renal tumors (p-value