Staff Members - Benha University
Recent Trend in the Chemistry of Triazolopyrimidines and their Applications
Mini-Reviews in Organic Chemistry • 2021
Publication Information
Authors
Mounir A. Salem, Mohamed S. Behalo and Rizk E. Khidre
Keywords
Triazolopyrimidine, pyrimidine, triazole, synthesis, heterocycles, pharmacological activities
Journal
Mini-Reviews in Organic Chemistry
Publisher
Bentham Scienc
Volume
18
Issue
1
Pages
1-16
publication.type
International
Paper Link
Not Available
Supplementary Materials
Mohamed Sayed Abd el-Rhman Sayed Behalo_article 2021.pdf
Abstract
This review deals with the synthetic methods, chemical reactions, and applications of triazolopyrimidine derivatives. The synthetic methods and chemical reactions are subdivided into groups
according to the junction between triazole and pyrimidine moieties for instance [1,2,4]triazolo[1,5-
a]pyrimidine, [1,2,4]triazolo[1,5-c]pyrimidine, [1,2,3]triazolo[1,5-a]pyrimidine, [1,2,3]triazolo[1,5-
c]pyrimidine, [1,2,4]triazolo[4,3-c]pyrimidine, and [1,2,4]triazolo[4,3-a]pyrimidine. Pharmacological
activity of triazolopyrimidins is also reported
according to the junction between triazole and pyrimidine moieties for instance [1,2,4]triazolo[1,5-
a]pyrimidine, [1,2,4]triazolo[1,5-c]pyrimidine, [1,2,3]triazolo[1,5-a]pyrimidine, [1,2,3]triazolo[1,5-
c]pyrimidine, [1,2,4]triazolo[4,3-c]pyrimidine, and [1,2,4]triazolo[4,3-a]pyrimidine. Pharmacological
activity of triazolopyrimidins is also reported