| publication name | Recent Trend in the Chemistry of Triazolopyrimidines and their Applications |
|---|---|
| Authors | Mounir A. Salem, Mohamed S. Behalo and Rizk E. Khidre |
| year | 2021 |
| keywords | Triazolopyrimidine, pyrimidine, triazole, synthesis, heterocycles, pharmacological activities |
| journal | Mini-Reviews in Organic Chemistry |
| volume | 18 |
| issue | 1 |
| pages | 1-16 |
| publisher | Bentham Scienc |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Mohamed Sayed Abd el-Rhman Sayed Behalo_article 2021.pdf |
Abstract
This review deals with the synthetic methods, chemical reactions, and applications of triazolopyrimidine derivatives. The synthetic methods and chemical reactions are subdivided into groups according to the junction between triazole and pyrimidine moieties for instance [1,2,4]triazolo[1,5- a]pyrimidine, [1,2,4]triazolo[1,5-c]pyrimidine, [1,2,3]triazolo[1,5-a]pyrimidine, [1,2,3]triazolo[1,5- c]pyrimidine, [1,2,4]triazolo[4,3-c]pyrimidine, and [1,2,4]triazolo[4,3-a]pyrimidine. Pharmacological activity of triazolopyrimidins is also reported