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Bio-based benzoxazines synthesized in a deep eutectic solvent: A greener approach toward vesicular nanosystems

Journal of Heterocyclic Chemistry • 2020
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Publication Information
Authors Mohamed S. Behalo1 | Ermelinda Bloise2 | Giuseppe Mele2 | Antonio Salomone3 | Francesco Messa3 | Luigi Carbone4 | Selma Elaine Mazzetto5 | Diego Lomonaco
Keywords Phthalazine, anticancer, antioxidant, MTT assay
Journal Journal of Heterocyclic Chemistry
Publisher Willey
Volume 57
Issue 1
Pages 1668-1773
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
A green synthesis of benzoxazines, based upon reaction of cardanol with formaldehyde and primary amines, is achieved in high yields using choline
chloride-urea mixture as deep eutectic solvent. Then, it is demonstrated how
the cardanol-based benxoxazines can be employed as only component for the
preparation of a nanovesicular systems