Aim: This compamtive stlldy wns designed to ('lln[lInte the efl!!cts of il/trat/,ecnl (IT) l~dellOsil1e . adlllinistered ill colljlll,clioll spillnllmpivncnille vlock ill patiellts IIJldergoillg vngillalhystrectolllies. Patients & Methods: The stl/dy collzprised 60 paticllts grollped according to the additive drllg iI/to: Grollp (5) sterile salille, grollp (M) Illorp/lille (250 )lg), grollp (A) ndellosille (500 J.lg) alld grollp (A&M) morp/tille (250 J.lg) with adellosille (500 J.lg). Paill scores were detemrillcd 2 hOllrly for 12 hOllrs alld 4 hOllrly for allotiter 1211 postopem tive/y usiJlg 10-poillts visllal /1l/n logllc sca Ie (VAS), dllrn tioJl of postopemtive aI/algesia, i.e., tillle elnpsed sillce elld of sllrgery till first reqllest of resclle aI/algesic (VAS=4) alld c1l1l1lllative IV telloxiwlIl conslllllptioJl WIIS reported. Results: Pntiel/ts received ndditive dmgs showed lower VAS scores t/I(lt were sigllificnllt iJl grollps (M) alld (A&M), Vllt 1I01l-sigllificallt ill grollp (A) ill cOlllparisoll to COil tro I grollp. The lIIeall dllratioll of postoperative allalgesia was siglllficallt/y (P