Staff Members - Benha University
Angiodysplasia and its correlation to serum magnesium level in patients with chronic kidney disease stage (5D) under maintenance hemodialysis
Journal of The Egyptian Society of Nephrology and Transplantation • 2022
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Journal of The Egyptian Society of Nephrology and Transplantation
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Local
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Abstract
Background
Angiodysplasias (ADs) are vascular ectasias not associated with any familial
syndrome, cutaneous lesions, or systemic vascular disease. They are the most
common vascular malformations of the gastrointestinal tract in the general
population with a prevalence of 0.82%. Most AD occurring in the general
population are detected in patients older than 60 years of age, although
presentation in patients with chronic kidney disease (CKD) can be earlier. The
aim was to correlate AD with serum magnesium level in patients with CKD stage 5D
under maintenance hemodialysis.
Patients and methods
This study included 60 patients with CKD stage 5D on maintenance hemodialysis.
Upper and lower gastrointestinal tract endoscopy was done for all patients in Kafr
Elsheikh University Hospital in a cross-sectional ‘prospective study,’ and all
laboratory investigations were done.
Results
The mean age of patients with CKD was 49.03±14.66 years. There was a
statistically significant increase in Mg among patients with AD and those without
AD. This study showed that there were statistically significant negative correlations
between Mg and parathyroid hormone.
Conclusion
AD is one of the common causes of gastrointestinal bleeding in all population and is
the most common cause of bleeding in patients with CKD. Hypermagnesemia is
associated with AD in patients with CKD
Angiodysplasias (ADs) are vascular ectasias not associated with any familial
syndrome, cutaneous lesions, or systemic vascular disease. They are the most
common vascular malformations of the gastrointestinal tract in the general
population with a prevalence of 0.82%. Most AD occurring in the general
population are detected in patients older than 60 years of age, although
presentation in patients with chronic kidney disease (CKD) can be earlier. The
aim was to correlate AD with serum magnesium level in patients with CKD stage 5D
under maintenance hemodialysis.
Patients and methods
This study included 60 patients with CKD stage 5D on maintenance hemodialysis.
Upper and lower gastrointestinal tract endoscopy was done for all patients in Kafr
Elsheikh University Hospital in a cross-sectional ‘prospective study,’ and all
laboratory investigations were done.
Results
The mean age of patients with CKD was 49.03±14.66 years. There was a
statistically significant increase in Mg among patients with AD and those without
AD. This study showed that there were statistically significant negative correlations
between Mg and parathyroid hormone.
Conclusion
AD is one of the common causes of gastrointestinal bleeding in all population and is
the most common cause of bleeding in patients with CKD. Hypermagnesemia is
associated with AD in patients with CKD