Chronic Kidney Disease (CKD) represents a significant public health problem, with nearly 20 million people in the United States having kidney damage or reduced kidney function, most patients with kidney disease are asymptomatic, underling the need for routine screening of all patients who are at risk for developing kidney disease. screening of chronic kidney disease among apparently healthy individuals in Kafr- Elsheikh university, Egypt. The parameters comprise :Full history taking including: personal history, past history, family history and drug history. Physical examination including: blood pressure, body weight, height and body mass index. And laboratory investigations as Serum creatinine, Urinary protein by dipstike and HbA1c. About 13.8% of apparently healthy subjects had CKD (62.2% had stage I, 33.8% had stage II, 4% had stage III). CKD was higher among males than females. Obesity was a risk factor for CKD and the percentage of obese among CKD patients was 48%, Class I obesity was 47.3%, Class II obesity 0.7%. Overweight 29.1% and normal weight 22.9%. The mean of BMI among CKD patients was 28.3± 4.2. Higher frequency of hypertension were significantly associated with CKD patients 33.8% when compared to non CKD subjects 5.1%. Diabetics was diagnosed among 5.6% of all studied subjects. Higher frequency of diabetics were significantly associated with CKD when compared to non CKD subjects. The percentage of CKD had diabetics was (26%) while CKD had pre diabetics was (25%) of CKD patients. Higher urinary protein grades were significantly associated with CKD.