Staff Members - Benha University
Evaluation of cardiac function in pediatric patients with mild to moderate bronchial asthma in the era of cardiac strain imaging
Pediatric Pulmonology • 2019
Publication Information
Authors
Gaser Abdelmohsen MD | Hossam Mohamed MD | Mona Mohsen MD |Osama Abdelaziz MD | Doaa Ahmed MSc | Mohamed Abdelsalam MD |Ahmed Dohain MD
Keywords
left ventricle strain, pediatric bronchial asthma, right atrial strain, right ventricle strain, speckle
tracking echocardiography
Journal
Pediatric Pulmonology
Publisher
Wiley Periodicals, Inc
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Abstract
Objective: Bronchial asthma is a common chronic inflammatory airway disease, which
may be associated with pulmonary hypertension and cardiac dysfunction. The aim of
this study was to evaluate the ability of 2D‐speckle tracking echocardiography (2DSTE)
and tissue doppler imaging (TDI) to detect subtle cardiac dysfunction in pediatric
patients with mild to moderate bronchial asthma.
Methodology: The study included 30 children with mild to moderate bronchial
asthma and 27 age‐matched healthy controls. Both groups underwent pulmonary
function tests, TDI and 2D‐STE. Myocardial performance index (MPI), S′, E′, A′
velocities, global strain of left ventricle (LV), right ventricle (RV), and right atrium (RA)
were measured.
Results: RV diastolic function was impaired in the patient group, as the tricuspid E′
velocity was significantly lower in the patients when compared with the controls (16
[14‐17] vs 16 [17‐19] cm/s, P = .044), while the RV‐MPI was significantly higher in
patients when compared to controls (0.30 [0.27‐0.36] vs 0.30 [0.30‐0.30], P = .001).
The global RV longitudinal strain, RA strain, and LV strain did not show significant
differences between the test and the control groups. RV systolic parameters and LV
systolic and diastolic parameters did not differ significantly between the two groups.
Conclusion: Pediatric patients with mild to moderate bronchial asthma may have
early RV diastolic dysfunction with preserved other cardiac functions.
Objective: Bronchial asthma is a common chronic inflammatory airway disease, which
may be associated with pulmonary hypertension and cardiac dysfunction. The aim of
this study was to evaluate the ability of 2D‐speckle tracking echocardiography (2DSTE)
and tissue doppler imaging (TDI) to detect subtle cardiac dysfunction in pediatric
patients with mild to moderate bronchial asthma.
Methodology: The study included 30 children with mild to moderate bronchial
asthma and 27 age‐matched healthy controls. Both groups underwent pulmonary
function tests, TDI and 2D‐STE. Myocardial performance index (MPI), S′, E′, A′
velocities, global strain of left ventricle (LV), right ventricle (RV), and right atrium (RA)
were measured.
Results: RV diastolic function was impaired in the patient group, as the tricuspid E′
velocity was significantly lower in the patients when compared with the controls (16
[14‐17] vs 16 [17‐19] cm/s, P = .044), while the RV‐MPI was significantly higher in
patients when compared to controls (0.30 [0.27‐0.36] vs 0.30 [0.30‐0.30], P = .001).
The global RV longitudinal strain, RA strain, and LV strain did not show significant
differences between the test and the control groups. RV systolic parameters and LV
systolic and diastolic parameters did not differ significantly between the two groups.
Conclusion: Pediatric patients with mild to moderate bronchial asthma may have
early RV diastolic dysfunction with preserved other cardiac functions.