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publication name Clinical, haematobiochemical and hair changes of goats with experimentally- induced copper deficiency with trials of treatment. Benha Vet Med. Journal. 23, (2): 137-147.
Authors Heba M. El-khaiat, Yassein, M. Abd El-Raof, Mohamed, M. Ghanem, Hossam, M. El-Attar, Hala, A. Abou-Zeina and Soad, M. Nasr
year 2012
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Abstract

This study was carried out on 16 adult castrated male Baladi goats with age ranged from 1-1.5 years old and weight range of 15-20 kg for clinical heamatological and biochemical evaluation of secondary induced copper deficiency in goats. They were randomized into 2 groups. The first group (6 goats) were apparently healthy and kept as control group, whereas the second group (10 goats) were subjected to experimental induction of secondary copper deficiency by dietary addition of Molybdenum ( MO; 10- 40 mg/kg DM) and Sulpher (S; 1.5-3 g / Kg dry matter) daily for 24 weeks. Blood samples were collected without anti-coagulant every 6 weeks for determination of serum copper, iron, and zinc in addition to ceruloplasmin activity. Heparinized blood samples were used for determination of erythrocyte superoxide dismutase (SOD) activity. Clinical examination of experimental induced hypocuperimic goats revealed changes in hair color and texture at the 9th week of the experiment. In addition, paleness of the conjunctival mucous membrane became evident at the 18th week of the experiment which considered a sign of anemia. Emaciation and loss of body condition became more obvious signs at the 24th week of the experiment. There was significant (P

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