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C-reactive protein in atopic and non atopic asthma in children

Tanta Medicl Journal • 2009
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Publication Information
Authors 21. Mohamed M Rashad, Mostafa Abd Elazeem, Elham A Mohammady, Ibrahim Abd Alaal
Keywords C-reactive protein, atopic and non atopic, asthma in children
Journal Tanta Medicl Journal
Publisher Fculty of Medicine, Tanta University
Volume 37
Issue 1
Pages 173-178
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Abstract
Objectives: this study aimed to investigate the relation between the C-reactive protein (CRP) levels and atopic and non-atopic Asthma in children.
Patients & Methods: the study included 20 healthy children (mean age 9.2 ±2.1 years) and 66 pediatric patients with asthma during the attack, atopic (n=30) and non-atopic (n=36), mean age `9.7±2.1 and 7.5±1.7 years respectively. CRP level was estimated to all children.
Results: serum CRP levels were significantly increased in patients with non-atopic asthma (39.2±19.8 mg/dl) compared with patients with atopic asthma (7.6± 4.1 mg/dl) and controls (5.2±2.1 mg/dl), with no significant difference between the later 2 groups.
Conclusion: Raised levels of CRP are significantly with non-oatopic asthma but not with atopic asthma in children. The increased CRP levels in non-atopic asthma support the theory that, in non-atopic asthma, there is not only a local but also an ongoing systemic inflammatory process.