Background:Immediate breast reconstruction has become in many medical centers the standard of care for women who need or desire surgical restoration of a breast mound after surgical excision of breast cancer. The shift from delayed to immediate reconstruction has occurred for many reasons including patient preference, lower cost, improved patient convenience, reduced anesthetic risk, and the lessened emotional trauma associated with immediate reconstruction (provided that not affecting adjuvant therapy ,so not affecting survival or increasing incidence of local recurrence) Aim:To report our experience in the role of thoracodorsal artery perforator flap in breast reconstruction as regard indications, contraindications, advantages and disadvantagesMethods: From December 2014 to Decemdre 2015, a total of 20 patients with early breast cancer who had been subjected to a prospective selective study with conservative breast surgery and immediate breast reconstruction.And follow up for a period of l.5 years post operatively for evidence of loco regional recurrence or distant failureResults:According to our scale evaluating outcome, Thoracodorsal artery perforator flap is effective method for immediate breast reconstruction with minimal post operative complications like seroma and flab necrosis. Conclusion:Our study confirmed that the results of Thoracodorsal artery perforator flap in breast reconstruction is satisfactory in selected motivated cases with acceptable cosmetic results and minor complications