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Intrathecal S(+)ketamine attenuates the spinal hypotensive and bradycardic effect of hyperbaric bupivacaine during spinal anesthesia for cesarean section
accepted in Ain-Shams Journal of Anesthesiology • 2015
Publication Information
Authors
MOHAMED ELRABIEY1 , MOHAMED ELSONBATY2
Keywords
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Journal
accepted in Ain-Shams Journal of Anesthesiology
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Abstract:
Objectives
In this work we evaluate the effect of addingS(+) ketamine to hyperbaric bupivacaine during spinal anesthesia for cesarean section as regards hypotension, bradycardia, duration of block, postoperative analgesia, side effects and Apgar scores
Materials and methods
Sixty patients scheduled for cesarean section under spinal anesthesia were studied in aprospective double-blinded randomized manner. Group A: 20 patients received 10 mg hyperbaric bupivacaine and another syringe contained normal saline considered the control group. Group B: 20 patients received 10 mg hyperbaric bupivacaine and another syringe contained 0.1 mg/kg S(+)katamine. Group C: 20 patients received 10 mg hyperbaric bupivacaine and another syringe contained 0.25 mg/kg S(+)katamine.
Results
The incidence of spinal hypotension and bradycardia is lower in S(+) ketamine groups,the duration of post operative sensory blockade is more prolonged in S(+)ketamine groups and there is decrease in the incidence of shivering in S(+) ketamine groups with no difference regarding motor blockade and Apgar scores.
Conclusion
S(+)Ketamine added to hyperbaric bupivacaine in spinal anesthesia for cesarean section provides more hemodynamic stability and prolongs the duration of postoperative analgesia with no prolongation of motor blockade besides a lower incidence of shivering.
Objectives
In this work we evaluate the effect of addingS(+) ketamine to hyperbaric bupivacaine during spinal anesthesia for cesarean section as regards hypotension, bradycardia, duration of block, postoperative analgesia, side effects and Apgar scores
Materials and methods
Sixty patients scheduled for cesarean section under spinal anesthesia were studied in aprospective double-blinded randomized manner. Group A: 20 patients received 10 mg hyperbaric bupivacaine and another syringe contained normal saline considered the control group. Group B: 20 patients received 10 mg hyperbaric bupivacaine and another syringe contained 0.1 mg/kg S(+)katamine. Group C: 20 patients received 10 mg hyperbaric bupivacaine and another syringe contained 0.25 mg/kg S(+)katamine.
Results
The incidence of spinal hypotension and bradycardia is lower in S(+) ketamine groups,the duration of post operative sensory blockade is more prolonged in S(+)ketamine groups and there is decrease in the incidence of shivering in S(+) ketamine groups with no difference regarding motor blockade and Apgar scores.
Conclusion
S(+)Ketamine added to hyperbaric bupivacaine in spinal anesthesia for cesarean section provides more hemodynamic stability and prolongs the duration of postoperative analgesia with no prolongation of motor blockade besides a lower incidence of shivering.