Staff Members - Benha University
Effect of magnesium on rotational thromboelastometry (ROTEM) and total blood products requirement in patients undergoing liver transplantation
Egyptian Journal Of Anaesthesia • 2012
Publication Information
Authors
Mohamed A. Hammouda a, Hisham S. Khedr b, Mohamed A. Alrabiey a, Ahmed M. AbdEl-Hamid a, Ahmed M. AbdEl-Azim a,* a Anesthesia & ICU Faculty of Medicine, Benha University, Egypt b Anesthesia & ICU Faculty of Medicine, Cairo University, Egypt
Keywords
Not Available
Journal
Egyptian Journal Of Anaesthesia
Publisher
Not Available
Volume
28
Issue
2
Pages
101 - 105
publication.type
Local
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Abstract Aim: This study aimed to assess the effect of Mg2+ therapy in improving ROTEM and
total blood products requirement during liver transplantation.
Patients and method: The study includes 30 patients suffering from end-stage liver disease with
MELD (model for end-stage liver disease) classification ranging from 15 to 24. The patients were
divided into two equal groups: Group I: The patients were given placebo (100 mL) normal saline
(NS). Group II: The patients were given 2 g Mg in 100 mL NS.
Results: In group II significant decrease in CT (clotting time) in EXTEM (which evaluates the
extrinsic pathway after addition of tissue factor), INTEM (which evaluates the intrinsic pathway
after contact activation), APTEM (assess fibrinolytic pathway) and FIBTEM (assess fibrinogen
level after tissue factor activation), decrease in clot formation time (CFT) in EXTEM, increase
a-angel (the angle determined from the reaction time to the inflection point of the amplitude of
the forming clot), in INTEM and FIBTEM and increase A10 (clot strength after 10 min) EXTEM,
FIBTEM and APTEM in comparison with group I.
* Corresponding author. Address: Benha University Hospital, Farid
nada st, Benha, Qalubia, Egypt. Tel.: +20 1002953928.
E-mail address: zazaanesthesia@yahoo.com (A.M. AbdEl-Azim).
1110-1849 ª 2012 Egyptian Society of Anesthesiologists. Production
and hosting by Elsevier B.V. All rights reserved.
Peer review under responsibility of Egyptian Society ofAnesthesiologists.
doi:10.1016/j.egja.2011.12.006
Production and hosting by Elsevier
Egyptian Journal of Anaesthesia (2012) 28, 101–105
Egyptian Society of Anesthesiologists
Egyptian Journal of Anaesthesia
www.elsevier.com/locate/egja
www.sciencedirect.com
total blood products requirement during liver transplantation.
Patients and method: The study includes 30 patients suffering from end-stage liver disease with
MELD (model for end-stage liver disease) classification ranging from 15 to 24. The patients were
divided into two equal groups: Group I: The patients were given placebo (100 mL) normal saline
(NS). Group II: The patients were given 2 g Mg in 100 mL NS.
Results: In group II significant decrease in CT (clotting time) in EXTEM (which evaluates the
extrinsic pathway after addition of tissue factor), INTEM (which evaluates the intrinsic pathway
after contact activation), APTEM (assess fibrinolytic pathway) and FIBTEM (assess fibrinogen
level after tissue factor activation), decrease in clot formation time (CFT) in EXTEM, increase
a-angel (the angle determined from the reaction time to the inflection point of the amplitude of
the forming clot), in INTEM and FIBTEM and increase A10 (clot strength after 10 min) EXTEM,
FIBTEM and APTEM in comparison with group I.
* Corresponding author. Address: Benha University Hospital, Farid
nada st, Benha, Qalubia, Egypt. Tel.: +20 1002953928.
E-mail address: zazaanesthesia@yahoo.com (A.M. AbdEl-Azim).
1110-1849 ª 2012 Egyptian Society of Anesthesiologists. Production
and hosting by Elsevier B.V. All rights reserved.
Peer review under responsibility of Egyptian Society ofAnesthesiologists.
doi:10.1016/j.egja.2011.12.006
Production and hosting by Elsevier
Egyptian Journal of Anaesthesia (2012) 28, 101–105
Egyptian Society of Anesthesiologists
Egyptian Journal of Anaesthesia
www.elsevier.com/locate/egja
www.sciencedirect.com