Comparative Study Between Fixed Dose of Hyperbaric Bupivacaine and Dose Related to Height Used in Spinal Anesthesia for Caesarean Section in Normal and Pre-Eclamptic Patients
• 2017
Publication Information
Authors
S. I. Saad 1
, E. El S. Afifi 1
, M. F. El Meligy 2
, D. H. Abd El Hameed and N. El-S. M. Amer 1
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publication.type
Local
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Abstract
Neuroaxial anesthesia has long been accepted as the standard practice for providing the safest anesthesia for
cesarean section .Spinal anesthesia for CS should ideally last the duration of the procedure without producing
maternal or fetal adverse effects. This study is to monitor the two techniques during cesarean section, fixed dose
of bupivacaine not tailored to patient height and variable dose of bupivacaine tailored to patient height. We will
compare the outcomes from the two different techniques regarding the level of anesthesia achieved, resulting
hemodynamics (BP & HR) ,the requirements for fluids & pressors ,development of nausea & vomiting and the
time needed to discharge from PACU. This study was conducted on 80 patients aged between 20 and 40 years
old, ASA grade I and ІІ . All patients were scheduled for elective cesarean section surgery. All cases were done
in Benha university Hospitals after approved consent from the patients. The duration of sensory and motor
block was significantly prolonged in fixed dose groups (A&C) than in adjusted dose groups (B&D).The
amount of fluids and vasopressors needed were significantly much more in fixed dose groups (A&C) than in
adjusted dose groups (B&D).The incidence of complications (hypotension , nausea and vomiting) were
significantly higher in fixed dose groups (A&C) than in adjusted dose groups (B&D).we have shown that
adjusting the dose of hyperbaric bupivacine (0.5%) according to height in both normal and pre-eclamptic
patients , in combination with opioids (fentanyl 20 mcq) , provide adequate anesthesia for elective cesarean
section in both normal and pre-eclamptic patients. This regimen associated with decrease in cephalic spread of
anesthesia, decrease incidence and severity of maternal hypotention ,nausea ,vomiting , decrease the amount of
fluids needed and the dosage of vasopressors used.
cesarean section .Spinal anesthesia for CS should ideally last the duration of the procedure without producing
maternal or fetal adverse effects. This study is to monitor the two techniques during cesarean section, fixed dose
of bupivacaine not tailored to patient height and variable dose of bupivacaine tailored to patient height. We will
compare the outcomes from the two different techniques regarding the level of anesthesia achieved, resulting
hemodynamics (BP & HR) ,the requirements for fluids & pressors ,development of nausea & vomiting and the
time needed to discharge from PACU. This study was conducted on 80 patients aged between 20 and 40 years
old, ASA grade I and ІІ . All patients were scheduled for elective cesarean section surgery. All cases were done
in Benha university Hospitals after approved consent from the patients. The duration of sensory and motor
block was significantly prolonged in fixed dose groups (A&C) than in adjusted dose groups (B&D).The
amount of fluids and vasopressors needed were significantly much more in fixed dose groups (A&C) than in
adjusted dose groups (B&D).The incidence of complications (hypotension , nausea and vomiting) were
significantly higher in fixed dose groups (A&C) than in adjusted dose groups (B&D).we have shown that
adjusting the dose of hyperbaric bupivacine (0.5%) according to height in both normal and pre-eclamptic
patients , in combination with opioids (fentanyl 20 mcq) , provide adequate anesthesia for elective cesarean
section in both normal and pre-eclamptic patients. This regimen associated with decrease in cephalic spread of
anesthesia, decrease incidence and severity of maternal hypotention ,nausea ,vomiting , decrease the amount of
fluids needed and the dosage of vasopressors used.
Staff Members - Benha University