Introduction: Study compares effect of adding epinephrine to bupivacine-fentyl mixture during spinal anesthesia for elective cesarean section in normotensive and pre-eclamptic parturients.
Methods: Twenty parturients who had given their consents and were scheduled for elective cesarean section under spinal anesthesia were divided into four groups first group contain five normotensive parturients received 0.5% hyperbaric bupivacine plus fentanyl, the second group also contain five normotensive parturients received 0.5% hyperbupivacine-fentanyl mixture plus epinephrine (0.2mg), the third group contain five severe pre-eclamptic parturients received hyperbaric bupivacine 0.5% plus fentanyl, the fourth group contain five severe pre-eclamptic parturients received hyperbaric bupivacine- fentanyl mixture plus epinephrine (0.2mg). The haemodynamics, anesthesia characteristics and adverse effects were observed.
Results: Mean heart rate didn't significantly differ between groups either A, B or C and D. there is difference in percentage of drop of mean blood pressure from baseline between group A, B (statistically significance) and drop in C, D (not statistically significance). The anesthesia onset time for sensory block significantly (P=0.03) prolonged in group B than in group A (4.6±1.14 vs 2.8±0.84minute) and the same in group D than group C (4.2± 0.45 vs 2.8±0.45min) (P= 0.005), the time of sensory block to regress below L1 was significantly (P