Objectives: To evaluate the predictivity of preoperative serum myocardial ischemia biomarkers for postoperative (PO) mortality in patients undergoing coronary artery bypass grafting (CABG) surgery. Patients & Methods: The study included 300 patients with mean age of 62.2±4.2 years. Patients were evaluated for preoperative risk factors and donated fasting blood samples for ELISA estimation of preoperative serum levels of creatinine (sCr), cardiac troponin T (cTnT) and cTnI and Creatine Kinase-myoband (CK-MB) Isoenzyme. Intraoperative and PO complications were determined. The 30-day PO mortality rate and total mortality rate at the end of follow-up period were determined. Results: All surgeries were conducted successfully without intraoperative mortalities or complications. One patient died during the 1st 30-days after surgery, 11 patients died during a mean follow-up period of 22 month for a follow-up mortality rate of 3.7% and a total mortality rate of 4%. Non-survivors were significantly (p