Staff Members - Benha University
ULTRASONIC EXAMINATIONS OF THE ENDOMETRIUM AND SERUM ESTRADIOL/PROGESTERONE RATIO AS PREDICTORS OF PREGNANCY RATE AFTER ICSI/ET CYCLES
• 2022
Publication Information
Authors
Mohamed A. ElNagga, Mohamed S.A.
Emarah, Mohamed Ibrahim
Ahmed, Abear El Shabacy.
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publication.type
Local
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Abstract
Objective: To determine whether or not endometrial thickness, echogenic pattern and E2/P ratio
measured on the day of embryo transfer can serve as reliable predictors of treatment outcome following
ICSI/ET cycles. Methods: A total of 367 infertile women undergoing embryo transfer after ICSI cycles were studied in a
prospective study. Ultrasound measurement of endometrial thickness on the day of hCG administration and on the day of ET
and E2/P ratio on the day of embryo transfer, hormonal prole (Day 3 FSH, LH and E2), and various other variables (age, BMI,
number of oocytes retrieved per patient, fertilization rate, number and quality of embryos) were evaluated. These variables
were compared among the clinical pregnancy, chemical pregnancy and non-pregnant groups. Also, their inuence on
implantation rate was examined. Results: There was no statistically signicant difference in the measured endometrial
thickness on the day of hCG administration (10.67 ± 2.25, 10.59 ± 2.18, 10.56 ± 2.22, P = 0.5) and that measured on the day of
embryo transfer among the three groups. The distribution of patients with type A endometrium among the clinical pregnancy Vs
the chemical pregnancy group (p=0.9) and that among the clinical pregnancy group Vs the non-pregnant group (p=0.14) was
statistically insignicant. The E2/P ratio was calculated and compared among the three groups, however the difference was
statistically insignicant (78.08 ± 85.27, 51.86 ± 44.81, 110.57 ± 274.49, p=0.65). Conclusion: Ultrasonographic features of the
endometrium (thickness and echo-pattern) and E2/P ratio cannot be used as reliable markers for endometrial receptivity in the
clinical setting.
ABSTRACT
KEYWORDS : Endometrial thickness, ech
measured on the day of embryo transfer can serve as reliable predictors of treatment outcome following
ICSI/ET cycles. Methods: A total of 367 infertile women undergoing embryo transfer after ICSI cycles were studied in a
prospective study. Ultrasound measurement of endometrial thickness on the day of hCG administration and on the day of ET
and E2/P ratio on the day of embryo transfer, hormonal prole (Day 3 FSH, LH and E2), and various other variables (age, BMI,
number of oocytes retrieved per patient, fertilization rate, number and quality of embryos) were evaluated. These variables
were compared among the clinical pregnancy, chemical pregnancy and non-pregnant groups. Also, their inuence on
implantation rate was examined. Results: There was no statistically signicant difference in the measured endometrial
thickness on the day of hCG administration (10.67 ± 2.25, 10.59 ± 2.18, 10.56 ± 2.22, P = 0.5) and that measured on the day of
embryo transfer among the three groups. The distribution of patients with type A endometrium among the clinical pregnancy Vs
the chemical pregnancy group (p=0.9) and that among the clinical pregnancy group Vs the non-pregnant group (p=0.14) was
statistically insignicant. The E2/P ratio was calculated and compared among the three groups, however the difference was
statistically insignicant (78.08 ± 85.27, 51.86 ± 44.81, 110.57 ± 274.49, p=0.65). Conclusion: Ultrasonographic features of the
endometrium (thickness and echo-pattern) and E2/P ratio cannot be used as reliable markers for endometrial receptivity in the
clinical setting.
ABSTRACT
KEYWORDS : Endometrial thickness, ech