Staff Members - Benha University
Genotoxic and histotoxic effects of air pollutants at a benzene station on albino rats
• 2014
Publication Information
Authors
ME Abou salem, Amer Elgerwi, A I ElMashad
Keywords
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Journal
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Publisher
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Volume
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Issue
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Pages
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publication.type
International
Paper Link
Open Link
Supplementary Materials
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Abstract
Background: This study was designed to explore the hazardous effects of occupational exposure to air pollutants arising from benzene stations.
Methods: A total of 48 albino rats were divided into three groups each of sixteen animals. Groups-I and II were kept at a benzene station for 60 and 120 days, respectively; while group-III was kept as a control under normal laboratory conditions. At the end of the experiment, animals were sacrificed and bone marrow samples were taken to investigate the effect of air pollutants at a benzene station on chromosomal aberrations and micronuclei formation. Tissue samples were also picked out to evaluate histotoxic effects of these air pollutants.
Methods: A total of 48 albino rats were divided into three groups each of sixteen animals. Groups-I and II were kept at a benzene station for 60 and 120 days, respectively; while group-III was kept as a control under normal laboratory conditions. At the end of the experiment, animals were sacrificed and bone marrow samples were taken to investigate the effect of air pollutants at a benzene station on chromosomal aberrations and micronuclei formation. Tissue samples were also picked out to evaluate histotoxic effects of these air pollutants.