Background: This study was designed to explore the hazardous effects of occupational exposure to air pollutants arising from benzene stations. Methods: A total of 48 albino rats were divided into three groups each of sixteen animals. Groups-I and II were kept at a benzene station for 60 and 120 days, respectively; while group-III was kept as a control under normal laboratory conditions. At the end of the experiment, animals were sacrificed and bone marrow samples were taken to investigate the effect of air pollutants at a benzene station on chromosomal aberrations and micronuclei formation. Tissue samples were also picked out to evaluate histotoxic effects of these air pollutants.