The construction of the High Aswan Dam (HAD) caused a dramatic reduction in fluvial discharge leading to an obvious footprint on the morphodynamics of the Nile River in Egypt (NRE). A typical erosional phase of undercutting and bed incising took place initially post-construction. Dredge work is carried out yearly at certain hot spots along the NRE course to allow for navigation. The present study focuses on the impact of dedicated dredging in alluvial rivers as a form of human interference. Numerical modeling was used to quantify volumes of erosion and deposition both with and without dredging within a 60 km reach downstream Isna Barrage (RK 167). Morphologic changes between 2004 and 2018 indicate net erosion where most of the material lost from bed is through dredging. The results suggest that dredging is altering the dynamic equilibrium of the current HAD flow release scheme.