This paper introduces a new technique for Key Generation based on fingerprints, Genetic Algorithms, and pseudorandom generator. The proposed technique can be applied in block ciphering techniques to enhance its performance (increase its complexity space). The paper introduces the different stages of the key generation sub-system; including preprocessing and features extraction to represent the fingerprints signature (ID). Secondly the computation of genetic biometric signature ID, the third stage is computation of the pseudorandom generator to generate the different keys for 3DES. Results analysis proved that; the generated keys were strong when compared with the weak or semi weak keys. The proposed key generation technique increases the key space as well as it increases the total overheads on the encryption system due to the extra operations added but these overheads can be neglected when compared with the strong generated keys and its high complexity space.