Staff Members - Benha University
Correlations Between Optical Coherence Tomography Angiography Parameters and the Visual Acuity in Patients with Diabetic Retinopathy
• 2020
Publication Information
Authors
Marwa AbdelshafyAhmed Abdelshafy
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publication.type
International
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Supplementary Materials
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Abstract
Aim: The aim of this study was to assess the correlation between different optical coherence
tomography angiography (OCTA) parameters and the best corrected visual acuity (BCVA) in
patients with diabetic retinopathy (DR).
Patients and Methods: Sixty eyes of 60 participants were included in this prospective
study: 40 diabetic patients [20 with non-proliferative diabetic retinopathy (NPDR group), 20
with proliferative diabetic retinopathy (PDR group)] and 20 age- and gender-matched normal
healthy subjects (control group). After full ophthalmological examination and fundus fluorescein
angiography, OCTA was performed for all participants. Quantitative OCTA parameters,
such as the foveal avascular zone (FAZ) area, the superficial capillary plexus vessel
density (%) (SCP-VD) and the deep capillary plexus vessel density (%) (DCP-VD) in, whole
and parafoveal areas were measured. Correlations between BCVA and OCTA parameters
were analyzed.
Results: There were no statistically significant differences between groups regarding age,
gender, refraction, macular thickness or intraocular pressure. The median (IQR) FAZ area
was 0.42 (0.39–0.46) mm2 in the NPDR group, 0.54 (0.45–0.65) mm2 in the PDR group and
0.24 (0.21–0.26) mm2 in the control group (P
tomography angiography (OCTA) parameters and the best corrected visual acuity (BCVA) in
patients with diabetic retinopathy (DR).
Patients and Methods: Sixty eyes of 60 participants were included in this prospective
study: 40 diabetic patients [20 with non-proliferative diabetic retinopathy (NPDR group), 20
with proliferative diabetic retinopathy (PDR group)] and 20 age- and gender-matched normal
healthy subjects (control group). After full ophthalmological examination and fundus fluorescein
angiography, OCTA was performed for all participants. Quantitative OCTA parameters,
such as the foveal avascular zone (FAZ) area, the superficial capillary plexus vessel
density (%) (SCP-VD) and the deep capillary plexus vessel density (%) (DCP-VD) in, whole
and parafoveal areas were measured. Correlations between BCVA and OCTA parameters
were analyzed.
Results: There were no statistically significant differences between groups regarding age,
gender, refraction, macular thickness or intraocular pressure. The median (IQR) FAZ area
was 0.42 (0.39–0.46) mm2 in the NPDR group, 0.54 (0.45–0.65) mm2 in the PDR group and
0.24 (0.21–0.26) mm2 in the control group (P