Treatment of non-union of the bone is a challenge, especially when the fracture is complicated by infection, angulation and translation, which is difficult to be managed by conventional methods. Here, we discuss the technique and the results of treatment of humeral non- union by the Ilizarov method. 20 patients with 20 humeral shaft nonunions were treated by debridement and fixation following the Ilizarov method. The mean age of the patients was 35.05±11.48 years, there were 13 males and 7 females. The mean follow up period was 16.2 months. The mean time in the frame was 8.1 months. Bony union was achieved in all patients. According to the A.S.A.M.I. Scale results were excellent in 13 patients (65%), good in 4 (20%), fair in 3 (15%). There were no poor results. The Ilizarov method is effective in various types of humeral non-union, provided a good understanding of the fracture requirements.