(AKI) frequently occurs in significant percentage of septic ICU critically ill patients with decimal prognosis. Early prediction of AKI and early interventions may improve outcome. The aim of this study is to examine if procalcitonin (PCT) can be used for early prediction of AKI septic patients in ICU. METHODS 67 patients with sepsis were enrolled in this study. On admission, PCT was measured together with serum creatinine, urea, and other inflammatory markers. qSOFA was calculated at the emergency department. Patients were classified into two groups: AKI and non-AKI groups. RESULTS PCT had a significantly higher value among patients who developed AKI than the non-AKI group (67.04±20.59 ng/ml vs. 36.84±18.36 ng/ml); p < 0.001. Also, PCT exhibited a good predictive role for AKI with the ROC area under the curve was. 0859 (p < 0.001).