The Effect of Liver Cirrhosis Severity on Left Ventricular Systolic and Diastolic Functions
Medical Journal Cairon Univ. • 2014
Publication Information
Authors
shaimaa mostafa, maha zein elabedin
Keywords
Liver cirrhosis — Severity — Left ventricular —Systolic — Diastolic — Function.
Journal
Medical Journal Cairon Univ.
Publisher
Not Available
Volume
32, No.2
Issue
Not Available
Pages
157 - 162
publication.type
Local
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Background: Alteration of cardiovascular functions in patients with liver cirrhosis has been described and it correlates with severity of hepatic failure. But cardiac function by conventional echocardiography has limitations and cardiac decompensation occurs when the heart is challenged.
Aim: To evaluate cardiac systolic and diastolic functions in patients with liver cirrhosis by conventional Doppler echocardiography and tissue Doppler image (TDI) and correlate the results with severity of cirrhosis based on Child-Pugh score.
Methods: 624 patients with liver cirrhosis divided into 3 groups according to Child pugh score then systolic and diastolic functions were evaluated with conventional echo (2D, PW Doppler and MM and by TD1 (Sm, Em and Am) then E/Em was calculated.
Results: By conventional echo LV dimensions and systolic function were normal and hyperdynamic in Child C, diastolic dysfunction was diagnosed in 67% and difference between 3 groups was insignificant, by TDI diastolic dysfunction was diaghosed in 89% in cirrhotic patients and there were statis-tically significant systolic dysfunction in the form of lower Sm (p=0.001) and there was significant +ve correlation between severity of cirrhosis and Sm and diastolic dysfunction in the form of lower Em (p=0.005) and there was significant +ve correlation between severity of cirrhosis and Em also higher E/Em (p=0.0001) with significant —ye correlation.
Conclusion: TDI is simple, non invasive, bedside, being cheap and more accurate test that can be used to detect early subclinical left ventricular systolic and diastolic dysfunction in cirrhotic patients especially in Child B cirrhosis.
Aim: To evaluate cardiac systolic and diastolic functions in patients with liver cirrhosis by conventional Doppler echocardiography and tissue Doppler image (TDI) and correlate the results with severity of cirrhosis based on Child-Pugh score.
Methods: 624 patients with liver cirrhosis divided into 3 groups according to Child pugh score then systolic and diastolic functions were evaluated with conventional echo (2D, PW Doppler and MM and by TD1 (Sm, Em and Am) then E/Em was calculated.
Results: By conventional echo LV dimensions and systolic function were normal and hyperdynamic in Child C, diastolic dysfunction was diagnosed in 67% and difference between 3 groups was insignificant, by TDI diastolic dysfunction was diaghosed in 89% in cirrhotic patients and there were statis-tically significant systolic dysfunction in the form of lower Sm (p=0.001) and there was significant +ve correlation between severity of cirrhosis and Sm and diastolic dysfunction in the form of lower Em (p=0.005) and there was significant +ve correlation between severity of cirrhosis and Em also higher E/Em (p=0.0001) with significant —ye correlation.
Conclusion: TDI is simple, non invasive, bedside, being cheap and more accurate test that can be used to detect early subclinical left ventricular systolic and diastolic dysfunction in cirrhotic patients especially in Child B cirrhosis.
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