The present study was designed to investigated the effect of four levels of copper oxychloride (0, 0.25, 0.50 and 0.75 LC50 ) on growth performance and feed utilization of Nile tilapia. Three levels of vitamin C (0, 1 an 2/ kg diet ) were used with each level of the fungicide to determine the effect of vitamin C in reducing the deleterious of fungicide, therefore twelve treatments were included in present study. At the end of the experiment after120 days, fungicide levels used in the present study showed adverse effect on all growth performance parameters of Nile tilapia studied. Final body weight, final body length, weight gain, specific growth rate and survival rate of fish decreased (almost significantly) with increasing the fungicide level. Whereas, vit. C had mostly, an increasing trend on the previous growth performance parameters of fish with increasing dietary vit. C level, but no significant differences were observed among dietary treatments, except that survival rate was significantly (P