Little is known about the use of coping intervention program which based on integrated care pathway (ICP) for mothers and their children with type 1diabetes mellitus (T1DM). Although parents of those children may experience stressful and difficult conditions, their participation in diabetes management has considered as an important indicator of positive health outcomes and positive coping. Aim: was to assess maternal coping intervention program based on integrated care pathway and its effect on glycemic control of their children with T1DM. Design: A quasi- experimental research was used. Setting: Diabetes Follow-up Clinic, Pediatrics Department at Benha University Hospital. Sample: Purposive sample of 50 mothers and their children with T1DM. Tools: Tool one; Characteristics of the mothers and their children and mothers' knowledge, Tool two; Way of Coping Scale and Tool three; Diabetic Self Care Activities Questionnaire. Results: Mean age of mothers 31.89± 5.21 years, more than one third of them had secondary and high education. About half of children their ages between 6